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Ok for the science geeks out there:
In our latest peer-reviewed publication, we analyzed a massive dataset examining SNP sequencing performance from skeletal remains. SNP profile completeness is driven primarily by the proportion of endogenous human DNA relative to background DNA, not by the classical degradation metrics developed for STR testing. Among samples that met a minimal human DNA threshold, more than 95 percent generated usable SNP profiles.
Advancing the scientific foundation of forensic genomics is a core objective at Othram. That's how we get more cases solved.
othram.com
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In our latest peer-reviewed publication, we analyzed a massive dataset examining SNP sequencing performance from skeletal remains. SNP profile completeness is driven primarily by the proportion of endogenous human DNA relative to background DNA, not by the classical degradation metrics developed for STR testing. Among samples that met a minimal human DNA threshold, more than 95 percent generated usable SNP profiles.
Advancing the scientific foundation of forensic genomics is a core objective at Othram. That's how we get more cases solved.
Large-Scale Analysis of DNA Quantification Metrics and SNP Sequencing Performance in Unidentified Human Remains | Othram Research
In a massive study of SNP profiling from skeletal remains, we find the profile completeness is strongly associated with human:non-human DNA ratio, whereas classical STR-derived metrics show little predictive value.
Sign up on our research page if you want technical updates on this sort of work!